ABSTRACT
Background: The coronavirus disease (SARS-COV-2) is an infectious disease caused by a coronavirus (Covid-19), which was first detected in clusters of pneumonia-like diseases in Wuhan City of china on December 31st, 2019. WHO already declared a global pandemic in April 2020 when this infection spread to more than 230 countries. Overall, 20-30 % of cases in the United States have required hospitalisation, resulting in a substantial burden on health care workers and the U.SHealth care system and other world economies including developed and developing countries like India. The Indian national expert group on vaccine administration for covid-19 (NEGVAC) will guide all aspects of covid-19 vaccine planning in India. In response to alleviate the severity of Covid-19 infection spread, our scientists have developed one vaccine with AstraZeneca collaboration, as Covishield and another Covaxin from serum institute. The aim is a prospective study on the effectiveness of the Covid-19 vaccine among health care providers. Aim(s): The study aims to describe the role of the vaccine in health care providers exposed to sars-cov-2 infection during the post-vaccination period of 6 months duration. The objective is to Primary To evaluate the efficacy of the Covid-19 vaccine among health care providers. Secondary - evaluation of the effectiveness of Covid-19 vaccine among different age groups of health care providers, detected Covid-19 positive by RT-PCR Test before vaccination. Evaluation of the effectiveness of covid-19 vaccine among a subgroup of Health care providers in which RT-PCR tests were found negative before vaccination. Material(s) and Method(s): This project was completed after covid-19 vaccines among exposed health care providers with and without prior history of covid-19 infection and followed up for a post-vaccination period of 6 months to assess the incidences of Covid-19 cases. The covid-19 vaccine intelligence network(CO-WIN) systems digital platform will be utilised to track the enlisted health care and frontline workers for vaccination and administration of vaccine on a real time basis. Result(s): The total number of RT-PCR confirmed cases among participants was 126(11%) out of 1140;which comprises of;in fully vaccinated, partially vaccinated and non-vaccinated participitants were 39(5.5%), 77(19.25%) and 10(26.31%) respectively. Conclusion(s): The covishield vaccine provides significant protection against the covid-19 infection, hence rapid vaccination along with other social measures likes hand sanitization, use of mask and social distancing are the most important weapons of humanity to fight this horrible disease named covid-19 Infection. Copyright © Necati Ozpinar. All rights reserved.